Geneticist David Sinclair on the Latest Anti-Aging Studies | Joe Rogan


Comments • 499

  • Sal Agnello
    Sal Agnello  1 days back

    @Joe, great interview, now what’s the inside scoop after you talked with David off air?

    • mark mclendon
      mark mclendon  1 days back

      David Sinclair is my guru, I've spent the last 4 months with a sublingual NMN under my tongue  ... I feel better but it fucks-up my Ketamine high

      • thomas seven
        thomas seven  2 days back

        Joe sure seems concerned with aging.

        • Lady Bohemia
          Lady Bohemia  3 days back

          You're as young as your spine. Do yoga.

          • Lady Bohemia
            Lady Bohemia  3 days back

            Apparently it will also make you look like a young Christian Slater.

            • heeheemanofHK
              heeheemanofHK  3 days back

              Obviously it's more complicated shit to live longer, so u need to pay this scammer money and buy his fucking book.

              Shit, when is it not about money with these white imperialist fucks

              • Persca99
                Persca99  4 days back

                You can blow me... 🤣🤣🤣

                • jedjust
                  jedjust  4 days back

                  could someone write up all the supplyments and amounts he mentioned and recommended? thanks

                  • C21H30O2
                    C21H30O2  4 days back

                    Tony Ferguson is type of guy who is not agin but leveling up

                    • Alastair Stephen
                      Alastair Stephen  4 days back

                      i feel my body will give in before I do; im 26 and been told many times i look around 16yo with a young and healthy mental state - id say im pretty intelligent and tend to think proactive about my fututre life, my endurance is on point while boxing/ on wind down i do a few power laps during swimming to keep the heart pumping then relax in the sauna i feel really fresh afterwords; but that is for the moment, my stress levels can be pretty high as living in a very fast paced and reactive city, I feel my body will decline faster than my mind and soul, so id be keen to know more about how i can get the most from this life and potential for extended lifespan??

                      • finnegan
                        finnegan  5 days back

                        Nah. Nah. Nah.

                        • yordano41
                          yordano41  5 days back

                          Just here for the comments.

                          • donald taylor
                            donald taylor  6 days back

                            Dairy makes me constipated I'll take mine with some nuts and seeds.

                            • Raki Jr
                              Raki Jr  6 days back

                              Rogan is just accelerating his aging by cruising test non stop. Ideally, you want to have as little androgenic activity as possible. It's the reason (although extreme) andy milonakis looks like a kid despite being 43.

                              • Jonathan Vaysman
                                Jonathan Vaysman  6 days back


                                • THOR GOD OF HAMMERS
                                  THOR GOD OF HAMMERS  6 days back

                                  The issue with Metformin reducing athletic performance could be that recent studies have shown it inhibits IGF-1 , studies also show that high IGF-1 is linked to shorter life spans in mice. This could be one of the reasons why Metformin lowers athletic performance but also increases life span.

                                  • Alset Alokin
                                    Alset Alokin  6 days back

                                    You don't look a day older than 49.5 Joe

                                    • Benjamin Thomas
                                      Benjamin Thomas  6 days back

                                      I take m n m,s every day. Just makes me fat

                                      • Vicky Biagini
                                        Vicky Biagini  7 days back

                                        Neighbor, the body does start breaking down in your fourties, believe me I'm there, and it's happening. Just don't get old, it really is that bad.

                                        • Salomia Petru
                                          Salomia Petru  7 days back


                                          • Ducky Darkstar
                                            Ducky Darkstar  7 days back

                                            I just saw him on good day new york in the morning plugging his book . He was wearing a suit and was killing it

                                            • Brendan Scully
                                              Brendan Scully  1 weeks back

                                              I'm taking Metformin everyday - and running a few times a week...but I'm not on the track team

                                              • Brendan Scully
                                                Brendan Scully  5 days back

                                                @Gori Brown I'm taking 1000 mg per day being a type 2 diabetic, and I'm seeing difference - I actually look better. I'm not taking a B12 supplement but I do eat eggs, dairy and fish, lamb, beef, chicken, all rich in B12 - I regularly drink fresh milk and a lot of water. I try to eat salad and vegetables. Doctors didn't say I needed a supplement and my bloods didn't suggest it. I'm 56 so I run and swim. I feel fine and think I'm in good condition for my age, cheers.

                                              • Gori Brown
                                                Gori Brown  5 days back

                                                How much mg ? Are you taking it because you're diabetic? Does it require vitb12 to take along.?

                                            • Josh Quintanilla
                                              Josh Quintanilla  1 weeks back

                                              Thoughts on methylene blue?

                                              • RampartDistric213
                                                RampartDistric213  1 weeks back

                                                So wait. Is Resveratrol bad for muscle gain? I am a bit confused

                                                • Lamo Content Gay
                                                  Lamo Content Gay  1 weeks back

                                                  As long as you don’t get a chronic illness you should be fine

                                                  • tygur23
                                                    tygur23  1 weeks back

                                                    Fuck metformin that shit is poison

                                                    • AxeKick80
                                                      AxeKick80  1 weeks back

                                                      We’re all gonna be LOTR elves.

                                                      • 02fire Jo
                                                        02fire Jo  4 days back

                                                        Exactly my thoughts 😂😂😂

                                                    • Hotpocket Moutaindew
                                                      Hotpocket Moutaindew  1 weeks back

                                                      Why didn't they just use metformin in Parasite Eve?

                                                      • J Mallett
                                                        J Mallett  1 weeks back

                                                        This is all bullshit

                                                        • zer0nix
                                                          zer0nix  1 weeks back

                                                          Fucking knew it. This is just like with nac, where taking the supplement nullified the benefits from doing exercise.

                                                          I think we're closing in on the signals the body uses to promote better health. What I want to know is, if one supplements with this stuff and it is interfering with the production of something else, how long does it take for the body to return to normal production levels, or is that suppressed forever like with steroids?

                                                          • koolerpure
                                                            koolerpure  1 weeks back

                                                            so my diabetes will make me look younger, thanks big pharma

                                                            • Smalltownbrewer1
                                                              Smalltownbrewer1  1 weeks back

                                                              Bunch of bullshit!

                                                              • Smalltownbrewer1
                                                                Smalltownbrewer1  1 weeks back

                                                                Human are so fucked up!! Metformin will fuck you up

                                                                • david bailey
                                                                  david bailey  1 weeks back

                                                                  Wouldn't you think rich people would reach out to his research company and do whatever they can to get results. It's crazy to believe that they don't have better funding

                                                                  • Sher Tard
                                                                    Sher Tard  1 weeks back

                                                                    Taking a bunch of steroids is not going to make you live longer

                                                                    • SulforaphaneMeUp
                                                                      SulforaphaneMeUp  1 weeks back

                                                                      Just for kicks I want to see on the next JRE David Sinclair and Diego Sanchez. That way Sinclair can take notes from the man who has turned back time.

                                                                      • Caelen Rene Cropper
                                                                        Caelen Rene Cropper  1 weeks back

                                                                        i like how sinclair isnt keeping it all to himself to sketchily sell the shnid to billionaires

                                                                        • IsDis FoReal
                                                                          IsDis FoReal  1 weeks back

                                                                          What is that powder he takes every day with his yogurt called?

                                                                          • Benami Ark
                                                                            Benami Ark  1 weeks back

                                                                            What did he say? "Metforeman" is found in blue violets?

                                                                            • Grim
                                                                              Grim  1 weeks back

                                                                              Wtf is up with these hate comments? Of course how old you will become is dependent on more factors than the age of your dna. That you should look after your body to prevent dying from cardiovascular disease or cancer should speak for itself. This guy just talks about the new science. And if you don't think your life is worth extending, you have other issues to deal with instead of judging here. Get on it!

                                                                              • Norman Osborn
                                                                                Norman Osborn  1 weeks back

                                                                                Metformin sells about go up

                                                                                • Yiannis
                                                                                  Yiannis  1 weeks back

                                                                                  Sinclair looks like a big lizard

                                                                                  • David Conway
                                                                                    David Conway  1 weeks back

                                                                                    This guy is creepy

                                                                                    • Norman Osborn
                                                                                      Norman Osborn  1 weeks back

                                                                                      That david goggins reference

                                                                                      • toplel kek
                                                                                        toplel kek  1 weeks back

                                                                                        Science is so cool

                                                                                        • john snow
                                                                                          john snow  1 weeks back

                                                                                          Have a chat with Tommy Robinson 👍

                                                                                          • Moe Makke
                                                                                            Moe Makke  1 weeks back

                                                                                            Ok what do I have to take ? Am I stealing my mother metformen or what????

                                                                                            • John M.
                                                                                              John M.  1 weeks back

                                                                                              Out live your money.